In one tweet she wrote, "I want @drake to murder my vagina."
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But when he failed to respond to her bizarre notes, Bynes began insulting his mother and his looks, insisting the rapper looks "ugly", "weird" and "disturbing".
And in one brutal tweet, she wrote, "I'm Getting Surgery To Fix My Nose. There's No Surgery That Fixes Drake's Ugly Downward Facing Eyes."
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She oddly followed the post by calling Drake "The Man Of My Dreams".The rapper has taken the high road in the Twitter drama but now he has addressed Bynes' comments for the first time in an interview with XXL magazine.
He says, "I don't even know who that is doing that or what that's about. If that is her, I guess it's a little weird and disturbing.
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"It's obviously a behavioural pattern that is way bigger than me. Whoever is behind it, whether it's her or somebody else, they know people are paying attention so they keep it going."Bynes is currently in a hospital in California under a two-week psychiatric hold after allegedly setting fire to a Thousand Oaks, California resident's driveway in July (13). Lawmakers and medics are carrying out a series of tests to determine if the star needs help with a reported mental health issue.